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Janumet 50/1000mg Tablet consists of the active ingredient Sitagliptin and Metformin. It is indicated in patients with type 2 diabetes mellitus. Type 2 diabetes is a condition in which the blood sugar (glucose) level is high in the body. It occurs when the body cells become resistant to the effect of insulin. As a result of this insulin resistance, the blood glucose level in the body increases. In type 2 diabetes, the body does not make sufficient insulin or the insulin that is produced is not used well. It is otherwise also known as non-insulin-dependent diabetes mellitus, and since it usually occurs past middle age, it is also widely referred to as mature onset diabetes.

If you have pancreatitis, gall stones, alcohol dependency, high levels of triglycerides, or type 1 diabetes , then inform your doctor before starting treatment with Janumet 50/1000mg Tablet. This medication is not to be taken by children and adolescents below the age of 18. Hypoglycemia (low blood sugar level), cough, runny or congested nose, and headache are some common side effects of this medication.


Uses of Janumet 50/1000mg Tablet:

  • SJanumet 50/1000mg Tablet is used to reduce the high blood sugar (glucose) levels in adult patients having type 2 diabetes.


Uses of Janumet 50/1000mg Tablet:

Janumet 50/1000mg Tablet works by regulating the blood glucose levels that usually increase post meals by stimulating insulin release from the pancreas. It prevents rapid degradation of glucagon-like peptides, leading to delayed gastric emptying, lower appetite, and controlled glucose fluctuation after meals.
Metformin decreases the production of glucose in the liver and decreases its absorption by the intestine.

Interaction with other drugs:

Inform your physician regarding any medicines you are taking or have taken before the treatment.


More Information:

Store between 20-25°C. Keep the medicines in a safe place away from the reach of children.


  1. Merck Sharp & Dohme (UK) Limited, Electronic Medicines Compendium (EMC), [Revised on February 2022] [Accessed on 9th august 2022], https://www.medicines.org.uk/emc/files/pil.564.pdf
  2. Merck Sharp & Dohme Corp., U.S. Food and Drug Administration, [Revised on] [Accessed on 9th august 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022044s022lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Hormones and Related Drugs, 7th edition, 2013, 274-276

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