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5 Flucel 250mg Injection contains the active ingredient Fluorouracil. It is an anti-cancer medication that treats cancer in the bowel, oesophagus, pancreas, stomach, head, neck, and breast. It may be used with other anti-cancer medicines and radiotherapy.


Nausea, vomiting, and bone marrow suppression are the most frequently occurring side effects associated with 5 Flucel 250mg Injection. Ensure that your physician conducts blood tests for you during and after this treatment to check the level of cells in your blood. Inform your physician before starting this treatment if you have undergone surgery in the last 30 days or if you are following a controlled sodium diet. 


If you're a male trying to become a father, you're advised to use contraception for up to 3 months after the treatment. Talk to your physician regarding sperm conservation before starting the treatment, as this 5 Flucel 250mg Injection might cause irreversible infertility. 


Uses of 5 Flucel 250mg Injection:

5 Flucel 250mg Injection is used to treat:

  • Colon and rectum cancer
  • Breast cancer
  • Gastric cancer
  • Pancreatic cancer
  • Head and Neck cancers
  • Oesophagus cancer
  • Anal cancer
  • Bladder cancer


How 5 Flucel 250mg Injection works:

5 Flucel 250mg injection gets activated after undergoing a series of enzymatic reactions. It forms a complex and interferes with DNA and RNA synthesis and function. This process affects the rapidly-growing cancer cells and inhibits cell growth.


Interaction with other drugs:

Inform your doctor about any medications you take or have taken before the treatment.


More Information:

  • Store protected from light at a temperature not exceeding 30°C.
  • Do not refrigerate or freeze.



  1. Spectrum Pharmaceuticals, Inc., US Food & Drug Administration, [Revised on Jul 2016] [Accessed on 25th May 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/012209s040lbl.pdf
  2. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on Jul 2020] [Accessed on 25th May 2022], https://www.medicines.org.uk/emc/files/pil.6041.pdf
  3. Edward Chu, Cancer Chemotherapy, Lange's Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
  4. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
  5. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on Nov 2021], [Accessed on 25th May 2022], https://www.medicines.org.uk/emc/files/pil.3790.pdf
  6. Jaffer A. Ajani, MD et al; Fluorouracil, Mitomycin, and Radiotherapy vs. Fluorouracil, Cisplatin, and Radiotherapy for Carcinoma of the Anal Canal; JAMA; Published on 23/04/ 2008; Accessed on 25/05/ 2022; https://jamanetwork.com/journals/jama/fullarticle/1028636
  7. Angélique Saint et al; Mitomycin and 5‐fluorouracil for second‐line treatment of metastatic squamous cell carcinomas of the anal canal; Cancer medicine; Published on 16th September 2019; Accessed on 25/05/ 2022; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853831/

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